Abstract:In order to explore the influence laws of the underground working environment in high-altitude mines on the safety human factor indexes and the causal process,based on the principles of safety engineering and the orthogonal analysis theory,the single factor and orthogonal composite factor tests were carried out with the help of the high-altitude environment simulation test system.The quantitative relationship between safety human factor indexes and mine environmental parameters was analyzed,and the statistical analysis software SPSS was used for the multiple regression analysis.A dynamic prediction model of various safety human factor indexes under the severe environmental conditions of high-altitude mines was constructed,and by comparing with the measured data,the reliability of the model was verified,three environmental factors,partial pressure of oxygen,temperature and humidity,have interactive effects on safety human factors.Research results provides a theoretical basis for work safety of the high-altitude mines.